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Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
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Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.
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Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
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Plant tissues are collections of similar cells performing related functions. Different plant tissues will have their own specialized roles and can be combined with other tissues to form organs such as flowers, fruit, stem, and leaves. Two major types of plant tissue include meristematic and permanent tissue.
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Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
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A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

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Soft tissue sarcoma in Asia.

Eileen Poon1, Richard Quek2

  • 1Division of Medical Oncology, National Cancer Centre Singapore, Singapore. eileen.poon.y.l@singhealth.com.sg.

Chinese Clinical Oncology
|September 4, 2018
PubMed
Summary
This summary is machine-generated.

Data on sarcoma epidemiology, treatment, and outcomes in Asia is scarce. Developing sarcoma centers of excellence and fostering collaboration are crucial for improving patient care and advancing research across the Asia-Pacific region.

Keywords:
Asia sarcomaadolescent and young adult cancer (AYA cancer)rare cancer in Asia

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Area of Science:

  • Oncology
  • Epidemiology
  • Healthcare Management

Background:

  • Sarcomas are rare mesenchymal malignancies affecting adults and adolescents/young adults (AYA).
  • Limited data exists on sarcoma epidemiology, treatment, and outcomes in the Asia-Pacific region compared to Western populations.
  • Lack of uniform guidelines and national registries hinders standardized care across Asia due to diverse healthcare structures and economic factors.

Purpose of the Study:

  • To highlight challenges and opportunities in sarcoma care within Asia.
  • To propose a vision for developing sarcoma centers of excellence (SCE) across Asia.
  • To identify areas for inter-center collaboration to advance sarcoma research.

Main Methods:

  • Review of existing literature and healthcare structures in the Asia-Pacific region.
  • Analysis of the need for standardized sarcoma care and specialized centers.
  • Conceptual framework for establishing and coordinating SCEs.

Main Results:

  • Significant data gaps exist regarding sarcoma in Asia.
  • Developing SCEs with multidisciplinary teams (MDTs) is vital for high-quality, sub-specialized care.
  • Collaboration is essential for knowledge sharing, education, and care coordination.

Conclusions:

  • Improving sarcoma care in Asia requires understanding regional macroeconomics and healthcare systems.
  • Establishing SCEs and expert MDTs is key to enhancing clinical outcomes.
  • Inter-center collaboration can drive advancements in sarcoma science and patient management throughout Asia.