Related Experiment Video
Updated: Feb 5, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
MRI Appearances of Colitis Cystica Profunda: A Rare Benign Mimicker of Colorectal Malignancy
Laiba Masood1, Sana Sayeed1, Maryam Asghar1
1Department of Radiology, Shifa International Hospital, Islamabad.
Abstract:
Colitis cystica profunda (CCP) is a rare benign disease characterised by mucin-filled cysts beneath the muscularis mucosae, which commonly involves the rectum and sigmoid colon. The disease process involving rectum is termed as proctitis cystica profunda. Trans-rectal ultrasound (TRUS) and magnetic resonance imaging (MRI) are an aid to diagnosis. However, histological analysis of deep biopsy is diagnostic. We report a case of 21-year male who presented with bleeding per rectum and was diagnosed as solitary ulcer of the rectum (SRUS) on superficial biopsies on sigmoidoscopy. Surgical intervention coupled with MRI findings and histopathological analysis formulated diagnosis of CCP. To our knowledge, we are second to report this entity with its MRI features.
Related Concept Videos
Brick Durability, Strength, and Appearance
Impression Management Techniques I: Managing Appearances
Drugs for Treatment of Ulcerative Colitis in IBD
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

