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Related Experiment Video

Updated: Feb 5, 2026

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery
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Hemostatic agent use in thyroid surgery: a meta-analysis.

Helmi Khadra1, Mohamed Bakeer2, Adam Hauch1

  • 1Division of Endocrine and Oncologic Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, LA, USA.

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|September 4, 2018
PubMed
Summary

Hemostatic agents in thyroid surgery offer minimal advantages for managing bleeding risk. While they may reduce drain output and hospital stays, they do not significantly lower hematoma or seroma risks compared to conventional methods.

Keywords:
Hemostatic agenthemostasisthyroid surgerythyroidectomy

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Area of Science:

  • Surgical Innovation
  • Medical Device Efficacy
  • Evidence-Based Medicine

Background:

  • Hemostatic agents are increasingly utilized in various surgical procedures.
  • Their application in thyroid surgery warrants a comprehensive safety and efficacy evaluation.
  • Conventional hemostasis techniques are standard but may have limitations.

Purpose of the Study:

  • To conduct a meta-analysis comparing hemostatic agents with conventional methods in thyroid surgery.
  • To assess the safety and efficacy of hemostatic agents based on current literature.
  • To evaluate key perioperative outcomes associated with their use.

Main Methods:

  • Systematic literature search of PubMed and EMBASE databases.
  • Inclusion of studies comparing hemostatic agents (gel, patch) to conventional hemostasis.
  • Extraction and statistical analysis of data on operative time, blood loss, hospital stay, and complications.

Main Results:

  • Ten studies totaling 941 patients were included in the meta-analysis.
  • Hemostatic agents did not significantly alter the risk of hematoma or seroma formation.
  • Significant reductions in drain output and hospital stay were observed with hemostatic agents.

Conclusions:

  • Hemostatic agents provide minimal benefits for perioperative bleeding risk management in thyroid surgery.
  • The observed benefits in drain output and hospital stay require further clinical consideration.
  • Further research may clarify the precise role of hemostatic agents in thyroidectomy.