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Updated: Feb 5, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
The effects of autoimmune blistering diseases on work productivity: A review
Esther Q Wang1,2,3, M Adriana Castrillón Velásquez2,3,4, Dedee F Murrell1,2,3
1Department of Dermatology, St George Hospital, Sydney, New South Wales, Australia.
Abstract:
This review examines the work productivity in patients with autoimmune blistering diseases (AIBDs). Work productivity and employment are important aspects of a patient's life, which can be affected by diseases. The Work Productivity and Activity Impairment Questionnaire (WPAIQ) is a validated instrument that can measure work productivity and assess the impact of disease on patients' work lives. There is currently a paucity of research that investigates the reason why AIBDs cause such a large impact on work productivity and whether AIBDs affect employment status. Using quality of life (QoL) instruments in conjunction with the creation of an adapted WPAIQ to examine the reasons behind work impairment may further characterize these effects and unveil a deeper understanding of stigmatization in the workplace as a factor of loss of work productivity.
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