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Updated: Feb 5, 2026

Fluorescent in situ Hybridization on Mitotic Chromosomes of Mosquitoes
Published on: September 17, 2012
Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
Mohammed Yusuf1,2, Kohei Kaneyoshi3, Kiichi Fukui3,4
1London Centre for Nanotechnology, University College London, London, WC1H 0AH, UK. ucanymo@ucl.ac.uk.
Abstract:
The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with improved sample preparations and image analyses should be adequately combined. This mini review highlights 3D imaging used for chromosome analysis so far with future imaging directions also highlighted.
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