Unravelling the hip pistol grip/cam deformity: Origins to joint degeneration

Paul E Beaulé1, George Grammatopoulos1, Andrew Speirs2

  • 1The Ottawa Hospital, 501 Smyth Road, Ottawa, Ontario, K1H 8L6.

Insights

Cam morphology, a hip deformity, is a significant cause of early hip osteoarthritis (OA) in some individuals. This 9-year study confirms the link and suggests interventions to prevent degeneration.

Area of Science:

  • Orthopaedic Surgery
  • Radiology
  • Biomechanical Engineering

Background:

  • Preexisting abnormal hip morphology is a risk factor for early hip osteoarthritis (OA).
  • Cam morphology, a type of femoroacetabular impingement, is implicated in hip degeneration.

Purpose of the Study:

  • To investigate the causal relationship between cam morphology and the development of hip OA.
  • To establish temporality, biological plausibility, and specificity of cam morphology as a cause of OA.

Main Methods:

  • Review of 9 years of research, including pediatric population studies.
  • In silico (finite element analysis) and in vivo (imaging biomarkers) investigations.
  • Assessment of Hill's criteria to determine causality.

Main Results:

  • A strong association was found between cam morphology, reduced range of motion, hip pain, and cartilage degeneration.
  • Temporality was established, with cam morphology preceding joint degeneration.
  • Biological plausibility and gradient were demonstrated, linking deformity degree to damage extent.

Conclusions:

  • Cam morphology is a cause of hip OA in susceptible individuals.
  • Interventions to remove cam morphology can positively influence the degenerative process.
  • Recommendations for screening, follow-up, and patient-specific assessment are proposed to prevent early joint degeneration.

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