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Related Concept Videos

Pancreas01:19

Pancreas

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The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
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Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

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The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
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Cells and Secretions of the Pancreas01:16

Cells and Secretions of the Pancreas

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The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
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Center of Gravity00:58

Center of Gravity

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The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
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Center of Gravity01:15

Center of Gravity

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The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
To determine its location, the principle of moments can be utilized by dividing the object into...
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Center of Mass00:59

Center of Mass

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The center of mass is the point at which the total mass of an object can be said to be concentrated. It is a fundamental principle in mechanics and physics that applies to all objects regardless of their shape or size. The center of gravity is the point at which an object’s weight appears to be concentrated and can be used to balance the object perfectly.
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...
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Related Experiment Video

Updated: Feb 5, 2026

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
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Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

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Almost 200 Pancreas Transplantations: A Single-Center Experience.

M Durlik1, K Baumgart-Gryn1

  • 1Department of Surgical Research and Transplantology, Mossakowski Medical Research Centre Polish Academy of Sciences, Warsaw, Poland; Clinical Department of Gastroenterological Surgery and Transplantation, Central Clinical Hospital of the Ministry of the Interior and Administration, Warsaw, Poland.

Transplantation Proceedings
|September 5, 2018
PubMed
Summary

Pancreas transplantation effectively treats diabetes by restoring insulin secretion and preventing complications. This study shows high patient and graft survival rates, demonstrating its value in specialized centers.

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Last Updated: Feb 5, 2026

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
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Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
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Area of Science:

  • Transplantation Surgery
  • Endocrinology
  • Nephrology

Background:

  • Pancreas transplantation is the most effective treatment for diabetes, restoring insulin secretion and metabolic balance.
  • It prevents life-threatening diabetic complications and reduces cardiovascular risk factors.
  • This procedure can halt the progression of chronic diabetic complications.

Purpose of the Study:

  • To evaluate the outcomes of pancreas transplantation.
  • To assess patient and graft survival rates.
  • To analyze the efficacy of different types of pancreas transplantations.

Main Methods:

  • Retrospective analysis of medical records for 193 pancreas transplantations.
  • Procedures included simultaneous pancreas-kidney (SPK), pancreas-alone (PTA), and pancreas-after-kidney (PAK) transplants.
  • Data collected from November 2004 to September 2017.

Main Results:

  • Overall patient survival was 87% at 1 year and 85% at 3-5 years.
  • Pancreas graft function rates were 72% at 1 year, decreasing to 63% at 5 years.
  • Kidney graft survival mirrored patient survival at 87% (1 year) and 85% (3-5 years).

Conclusions:

  • Pancreas transplantation is an established treatment for long-standing diabetes.
  • It is a complex procedure requiring expertise and a multidisciplinary approach.
  • High complication rates necessitate performance in highly specialized centers.