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Updated: Feb 5, 2026

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
Published on: July 27, 2022
Almost 200 Pancreas Transplantations: A Single-Center Experience
1Department of Surgical Research and Transplantology, Mossakowski Medical Research Centre Polish Academy of Sciences, Warsaw, Poland; Clinical Department of Gastroenterological Surgery and Transplantation, Central Clinical Hospital of the Ministry of the Interior and Administration, Warsaw, Poland.
Introduction:
Pancreas transplantation is the most effective and physiological method of treatment of patients with diabetes. It restores proper insulin secretion and helps to achieve a metabolic balance by eliminating the need for exogenous insulin. It can also prevent life-threatening diabetic complications. Pancreas transplantation can also reduce cardiovascular risk factors and can prevent the evolution of some of the chronic diabetic complications.
Patients And Methods:
From November 2004 until September 2017, 193 pancreas transplantations were performed in the Clinical Department of Gastroenterological Surgery and Transplantation in Central Clinical Hospital of the Ministry of the Interior and Administration in Warsaw. All medical records of the recipients who underwent pancreas transplantation in our center were retrospectively analyzed.
Results:
Among 193 transplantations, we performed 159 simultaneous pancreas kidney transplantations (SPK), 25 pancreas transplantations alone (PTA), and 9 pancreas after kidney transplantations (PAK). The overall patient survival was 87% at 1 year and 85% at 3 and 5 years after transplantation. At 1 year after transplantation, 72% patients had a fully functioning pancreas graft; at 3 years, 68%; and at 5 years, 63%. Kidney graft survival was 87% at 1 year and 85% at 3 and 5 years after transplantation.
Conclusions:
Pancreas transplantation is an established treatment for long-lasting diabetes. It is a complicated procedure, which requires experience and multidisciplinary approach. It is an operation with a relatively high complication rate and should be performed in highly specialized centers.
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