Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functions of Smooth Muscles01:23

Functions of Smooth Muscles

3.4K
Smooth muscles are an important type of muscle tissue that plays a vital role in the involuntary movements of internal organs. For example, they help regulate the movement of food through the gut and the flow of blood through the circulatory system.
Function of visceral smooth muscles
Visceral smooth muscle is found in the walls of all hollow organs, except the heart, and is a key player in the involuntary movements that drive the functioning of these internal organs. This tissue is arranged in...
3.4K
Smooth Muscle Contraction01:25

Smooth Muscle Contraction

7.8K
Smooth muscle contraction is a complex process vital for various bodily functions, from maintaining blood vessel tension to facilitating the movement of food through the digestive tract. Unlike striated muscles, smooth muscle contraction begins more slowly and lasts longer.
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...
7.8K
Structure and Organization of Smooth Muscles01:13

Structure and Organization of Smooth Muscles

8.7K
Smooth muscle tissue is a type of muscle tissue that can be found lining various vital organs in the human body, including the lungs, blood vessels, digestive tract, and respiratory tract. This type of tissue is responsible for regulating the movements of these organs, playing crucial roles in the functioning of various systems, including the vascular, digestive, respiratory, and urinary systems.
Structure of smooth muscle cell
Smooth muscle cells are spindle-shaped with tapering ends and a...
8.7K
Plant Cell Wall02:43

Plant Cell Wall

60.4K
The plant cell wall gives plant cells shape, support, and protection. As a cell matures, its cell wall specializes according to the cell type. For example, the parenchyma cells of leaves possess only a thin, primary cell wall.
60.4K
Plant Cell Wall01:07

Plant Cell Wall

7.7K
Plant cells have a cell wall, a rigid outer covering that protects the cell and provides shape and support. During cell division, a mixture of enzymes, proteins, and glucose molecules is transported via vesicles to the center of the cell. These vesicles continuously fuse and build a cell plate between the dividing cells. As the cell plate matures, new polysaccharides are added to it to form the cell walls of the daughter cells. The predominant polysaccharide in the cell wall is cellulose, made...
7.7K
Decreasing Function01:27

Decreasing Function

299
A decreasing function describes a relationship where the output consistently declines as the input increases. This means that for any two input values, if one is greater than the other, the corresponding output is smaller. Mathematically, a function f is decreasing on an interval I if for every x1 < x2​ in I, f (x1) > f (x2). This type of behavior is visually identified on a graph that slopes downward from left to right.The nature of a function can be analyzed by calculating...
299

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retrospective Evaluation of an Artificial Intelligence-Assisted Video Laryngoscope System for Tracheal Intubation in Infants and Neonates.

Paediatric anaesthesia·2026
Same author

ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport.

Nature communications·2026
Same author

Congenital hypoganglionosis: phenotype-based outcomes and evolution of diagnosis and management-a systematic review.

Pediatric surgery international·2026
Same author

Direct electrochemical amidation of fatty acids with ammonia in liquefied ammonia.

Chemical communications (Cambridge, England)·2026
Same author

UniEgoMotion: A Unified Model for Egocentric Motion Reconstruction, Forecasting, and Generation.

Proceedings. IEEE International Conference on Computer Vision·2026
Same author

A multi-regional survey of empathy and its associated factors among community pharmacists within a national pharmacy network in Japan.

Scientific reports·2026

Related Experiment Video

Updated: Feb 5, 2026

Isolation of Murine Coronary Vascular Smooth Muscle Cells
08:24

Isolation of Murine Coronary Vascular Smooth Muscle Cells

Published on: May 30, 2016

14.8K

Does Vascular Endothelial Cell or Smooth Muscle Affect the Decrease in Oxygen Consumption of Arteriolar Wall During

Masahiro Shibata1, Tomohiro Komine2, Yuki Maeda2

  • 1Department of Bioscience and Engineering, Shibaura Institute of Technology, Tokyo, Japan. shibatam@sic.shibaura-it.ac.jp.

Advances in Experimental Medicine and Biology
|September 5, 2018
PubMed
Summary
This summary is machine-generated.

Vascular wall oxygen consumption decreases during vasodilation, regardless of endothelial cells or smooth muscle. This reduction is linked to less mechanical work by vascular smooth muscle, not changes in energy efficiency.

More Related Videos

Isolation of Intrapulmonary Artery and Smooth Muscle Cells to Investigate Vascular Responses
07:56

Isolation of Intrapulmonary Artery and Smooth Muscle Cells to Investigate Vascular Responses

Published on: June 8, 2022

4.8K
Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry
07:17

Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry

Published on: October 30, 2019

7.2K

Related Experiment Videos

Last Updated: Feb 5, 2026

Isolation of Murine Coronary Vascular Smooth Muscle Cells
08:24

Isolation of Murine Coronary Vascular Smooth Muscle Cells

Published on: May 30, 2016

14.8K
Isolation of Intrapulmonary Artery and Smooth Muscle Cells to Investigate Vascular Responses
07:56

Isolation of Intrapulmonary Artery and Smooth Muscle Cells to Investigate Vascular Responses

Published on: June 8, 2022

4.8K
Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry
07:17

Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry

Published on: October 30, 2019

7.2K

Area of Science:

  • Physiology
  • Vascular Biology
  • Cellular Metabolism

Background:

  • In vivo arteriolar oxygen consumption rate (QO2) exceeds isolated segment values.
  • Vascular wall QO2 decreases during vasodilation.
  • The specific cell type (endothelial or smooth muscle) responsible for this QO2 reduction is unclear.

Purpose of the Study:

  • To determine if vascular endothelial cells (ECs) or smooth muscle cells drive the decrease in vascular wall QO2 during vasodilation.
  • To investigate the roles of EC-dependent and EC-independent vasodilation in vascular oxygen consumption.

Main Methods:

  • Utilized phosphorescence quenching microscopy to measure intra- and peri-vascular PO2 in rat cremaster muscle arterioles.
  • Induced EC-dependent vasodilation via increased NO production (simulating increased blood flow).
  • Induced EC-independent vasodilation using topical papaverine administration.

Main Results:

  • Both EC-dependent and EC-independent vasodilation significantly decreased vascular wall QO2 compared to normal conditions.
  • EC-independent vasodilation showed a lower vascular wall QO2 than EC-dependent vasodilation.
  • Energy efficiency (mechanical work vs. QO2) remained unchanged during vasodilation, suggesting reduced mechanical work.

Conclusions:

  • The reduction in vascular wall QO2 during vasodilation is primarily associated with decreased mechanical work by vascular smooth muscle.
  • Both endothelial and smooth muscle contributions are involved in the overall decrease of vascular oxygen consumption during vasodilation.
  • Findings highlight the dynamic metabolic adjustments within the vascular wall during changes in blood flow and vessel tone.