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Updated: Feb 5, 2026

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
Published on: August 11, 2012
Sarcoidosis of the fallopian tube: A rare case study with confirmed Propionibacterium acnes infection
Takashi Kuno1, Masahito Tachibana1, Soshi Muramatsu2
1Department of Obstetrics and Gynecology, Tohoku University Hospital, Sendai, Japan.
Abstract:
Sarcoidosis is a systemic granulomatous disease that is most commonly manifested in the pulmonary system. Though the entire etiology of sarcoidosis remains unknown, it has been reported that Propionibacterium acnes (P. acnes) has been isolated from sarcoid lesions. Herein, we report a case of salpingitis arising from sarcoidosis. A female patient aged 37 years, gravida 2 para 0, who had been diagnosed with sarcoidosis at the age of 36 years, underwent laparoscopic right salpingectomy due to obvious right hydrosalpinx with recurrent refractory right lower abdominal pain. The pathological diagnosis was granulomatous salpingitis of the right fallopian tube suspecting sarcoidosis. Immunocytochemistry using a specific monoclonal antibody against P. acnes lipoteichoic acid (PAB antibody) revealed PAB-positive reaction in sarcoid granuloma. This is the first case of sarcoidosis that the presence of P. acnes was shown in sarcoid lesions in the fallopian tube.
Insights
This study reports a rare case of salpingitis caused by sarcoidosis in a 37-year-old woman. Propionibacterium acnes (P. acnes) was identified in the fallopian tube sarcoid lesions, suggesting a potential role in the disease.
Area of Science:
- Reproductive Medicine
- Infectious Diseases
- Immunology
Background:
- Sarcoidosis is a systemic granulomatous disease primarily affecting the lungs.
- The etiology of sarcoidosis is not fully understood, but Propionibacterium acnes (P. acnes) has been implicated in some cases.
- Gynecological manifestations of sarcoidosis are uncommon.
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