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Updated: Feb 5, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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A study on related factors of hemodynamic depression in carotid artery stenting

J Liu1, Z-Q Xu, X Yi

  • 1Department of Neurology and Center for Clinical Neuroscience, Daping Hospital, Third Military Medical University, Chongqing, P.R. China. zhouhd@163.com.

European Review for Medical and Pharmacological Sciences
|September 5, 2018
PubMed

Insights

Carotid artery stenting (CAS) can lead to hemodynamic depression (HD). Using temporary cardiac pacemakers during CAS may help reduce HD and major adverse perioperative cardiovascular events (MACCE).

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Carotid artery stenting (CAS) is a common procedure for treating carotid artery stenosis.
  • Hemodynamic depression (HD) is a potential complication following CAS.
  • Understanding the factors contributing to HD is crucial for improving patient outcomes.

Purpose of the Study:

  • To investigate the pathogenesis and related factors of hemodynamic depression (HD) after carotid artery stenting (CAS).
  • To evaluate the effectiveness of temporary cardiac pacemakers in managing HD and reducing perioperative complications.

Main Methods:

  • A retrospective study of 433 patients undergoing CAS between January 2013 and June 2016.
  • Establishment of diagnostic criteria for HD in CAS patients.
  • Analysis of cerebral angiography, carotid plaque morphology, and the use of temporary cardiac pacemakers.
  • Classification of patients into HD and non-HD groups for comparative analysis.

Main Results:

  • 59.80% of patients (241/433) developed HD after CAS.
  • No significant difference in HD prevalence was observed between groups, except for a higher incidence in patients with diabetes.
  • Bilateral CAS was associated with a significantly higher incidence of HD (p<0.05).
  • The HD group experienced a higher number of major adverse perioperative cardiovascular events (MACCE) (31 vs. 2).

Conclusions:

  • Temporary cardiac pacing may be an effective strategy to mitigate HD after CAS.
  • Utilizing temporary cardiac pacemakers could potentially reduce perioperative MACCE in patients undergoing CAS.
Abstract

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