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Outcomes in patients with Hirschsprung disease following definitive surgery

Gunadi1, Stefani Melisa Karina2, Andi Dwihantoro2

  • 1Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr, Sardjito Hospital, Jl. Kesehatan No. 1, Yogyakarta, 55281, Indonesia. drgunadi@ugm.ac.id.

BMC Research Notes
|September 6, 2018
PubMed

Insights

Transanal endorectal pull-through (TEPT) is the most common surgery for Hirschsprung disease (HSCR) in Indonesian children. Posterior neurectomy increases constipation risk compared to other HSCR surgical procedures.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Congenital Disorders

Background:

  • Hirschsprung disease (HSCR) is a congenital condition affecting the large intestine.
  • Various surgical pull-through procedures exist for HSCR treatment.
  • Outcomes of these procedures can vary significantly.

Purpose of the Study:

  • To evaluate surgical outcomes in pediatric HSCR patients.
  • To analyze procedures performed at Dr. Sardjito Hospital, Indonesia.
  • To identify factors influencing HSCR treatment outcomes.

Main Methods:

  • Retrospective analysis of 67 HSCR patients under 18 years old.
  • Data collected from January 2013 to December 2014.
  • Surgical procedures analyzed include transanal endorectal pull-through (TEPT), Soave, and Duhamel.

Main Results:

  • Most patients (85%) presented neonatally with short-segment HSCR.
  • TEPT was the most frequent procedure (54%).
  • Constipation rates were significantly higher after posterior neurectomy (OR=15.5, p=0.019).

Conclusions:

  • Neonatal diagnosis and TEPT are common for HSCR in Indonesia.
  • Posterior neurectomy is associated with an increased risk of constipation post-surgery.
  • Further research may optimize surgical techniques for HSCR.
Abstract

Keywords:
ConstipationDefinitive surgeryEnterocolitisHirschsprung disease

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