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Transcatheter aortic valve implantation: Update in 2018
Nils Perrin1, Angela Frei1, Stephane Noble1
1Structural Cardiology Unit, Division of Cardiology, Department of Medical Specialties at the University Hospital of Geneva, Switzerland.
Transcatheter aortic valve implantation (TAVI) is now standard for high-risk aortic stenosis patients and an option for intermediate-risk cases, showing improved outcomes and reduced mortality.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Transcatheter aortic valve implantation (TAVI) has evolved significantly over 15 years.
- It is now the standard of care for high-risk symptomatic aortic stenosis patients.
- TAVI is increasingly considered for select intermediate-risk patients due to improved outcomes.
Purpose of the Study:
- To provide internists with current data on TAVI clinical outcomes.
- To highlight remaining challenges and evidence gaps in TAVI.
- To inform improvements in clinical practice and expansion of TAVI indications.
Main Methods:
- Review of recent major clinical trials on TAVI.
- Analysis of safety and clinical outcomes data.
- Assessment of technological advancements and operator experience.
Main Results:
- TAVI demonstrates good, reproducible clinical and safety outcomes.
- Significant reductions in procedure-related complications and long-term mortality.
- Technological improvements and increased operator experience contribute to success.
Conclusions:
- TAVI has surpassed conventional surgery for high-risk patients.
- Further research is needed to address TAVI pitfalls and evidence gaps.
- Optimizing TAVI practice will improve patient care and broaden its application.
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