Related Experiment Video
Updated: Feb 5, 2026

Immunostimulatory Agent Evaluation: Lymphoid Tissue Extraction and Injection Route-Dependent Dendritic Cell Activation
Published on: September 16, 2018
Routes of Antigen Injection in Rabbits
Abstract:
The route of antigen injection is guided by three practical decisions: (1) the volume to be delivered, (2) the buffers and other components to be injected with the immunogen, and (3) how quickly the immunogen should be released into the lymphatics or circulation. For rabbits, large-volume injections normally are given at multiple subcutaneous sites. If adjuvants or particulate matter are included in the injection, the immunogen should not be delivered intravenously. If slow release of the inoculum is desired, the injections should be performed either intramuscularly or intradermally. For immediate release, use intravenous injections.
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