Related Experiment Video
Updated: Feb 5, 2026
Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
NCCN Guidelines Insights: Bladder Cancer, Version 5.2018
Abstract:
The NCCN Clinical Practice Guidelines in Oncology for Bladder Cancer provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with bladder cancer. These NCCN Guidelines Insights discuss important updates to the 2018 version of the guidelines, including implications of the 8th edition of the AJCC Cancer Staging Manual on treatment of muscle-invasive bladder cancer and incorporating newly approved immune checkpoint inhibitor therapies into treatment options for patients with locally advanced or metastatic disease.
Insights
The NCCN updated bladder cancer guidelines incorporate the 8th edition AJCC staging for muscle-invasive bladder cancer. New immune checkpoint inhibitors are now included for advanced or metastatic bladder cancer treatment.
Area of Science:
- Oncology
- Urology
- Clinical Practice Guidelines
Background:
- The National Comprehensive Cancer Network (NCCN) provides guidelines for bladder cancer management.
- The 2018 guidelines require updates to reflect advancements in staging and therapy.
Purpose of the Study:
- To summarize key updates to the NCCN Bladder Cancer Guidelines.
- To highlight the impact of the 8th edition AJCC Cancer Staging Manual.
- To integrate new immune checkpoint inhibitor therapies into treatment recommendations.
Main Methods:
- Review of the NCCN Clinical Practice Guidelines in Oncology for Bladder Cancer.
- Analysis of updates from the 2018 version.
- Inclusion of AJCC 8th edition staging implications.
- Incorporation of newly approved immune checkpoint inhibitor data.
Main Results:
- The 8th edition AJCC staging manual impacts muscle-invasive bladder cancer treatment.
- Immune checkpoint inhibitors are now recommended for advanced or metastatic bladder cancer.
- Updated guidelines provide a revised framework for bladder cancer care.
Conclusions:
- The NCCN guidelines provide crucial updates for bladder cancer diagnosis and treatment.
- These revisions ensure optimal patient management based on the latest evidence and staging.
- The integration of novel therapies like immune checkpoint inhibitors represents a significant advancement.
Related Concept Videos
01:11Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
01:30Guidelines for Nursing Documentation I
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
01:23Guidelines for Sketching a Curve
01:26Guidelines for Nursing Documentation II
Timely documentation is crucial to ensure continuity of care for patients. Any delays in recording or reporting medical information can result in medical errors and even adverse patient outcomes. From medication administration to diagnostic test results, every detail must be accurately and promptly documented to provide the best possible care for patients.
01:06Legal Guidelines for Documentation
01:23Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...