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Published on: December 19, 2017
Clinical implication of spontaneous gastrointestinal perforation in pediatric patients: its difference according to
Young-Jin Choi1, Yong-Hoon Cho1,2, Soo-Hong Kim1
1Department of Surgery, Pusan National University Yangsan Hospital, Yangsan, Korea.
Insights
Spontaneous gastrointestinal perforations (SGIPs) in children show varied features by age, with neonates having more stomach and small intestine issues. Prompt treatment is key for good outcomes in all pediatric patients.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Clinical Medicine
Background:
- Spontaneous gastrointestinal perforations (SGIPs) are rare in children.
- Understanding age-specific patterns is crucial for effective management.
Purpose of the Study:
- To define age-specific features of SGIPs in pediatric patients.
- To compare clinical characteristics between neonates and older children.
Main Methods:
- Retrospective review of surgical cases of SGIPs in children.
- Comparison of patient characteristics between neonates (Group A) and beyond neonates (Group B).
Main Results:
- SGIPs occurred in the stomach, small intestine, and large intestine.
- Neonates had more stomach/small intestine perforations, while older children had more large intestine perforations (P=0.01).
- Overall mortality was 15.4%, with no significant difference based on age or perforation site.
Conclusions:
- Pediatric SGIPs present diverse features and age-related perforation patterns.
- Prompt recognition, resuscitation, and surgery are vital for favorable outcomes.
- Age group did not significantly impact mortality rates.
Purpose:
Spontaneous gastrointestinal perforations (SGIPs; not associated with injury or disease) occur rarely in pediatric patients. This study aimed to define age-specific features associated with SGIPs in pediatric patients.
Methods:
Retrospectively reviewed the clinical data of children (before adolescence) who received surgery due to a SGIP at a single institution. Thirty-nine patients were enrolled. Characteristics were compared between the 2 age groups: neonates (group A) and beyond neonates (group B).
Results:
Group A included 24 patients (61.5%) an group B included 15 patients (38.5%). Thirteen perforations occurred in the stomach (33.3%), 12 in the small intestine (30.8%), and 14 in the large intestine (35.9%). A significantly higher proportion of perforations occurred in the stomach and small intestine in group A, while more perforations occurred in the large intestine in group B (P = 0.01). Several associated conditions during the preoperative period were identified in both groups. The overall mortality rate was 15.4% (6 of 39). Mortality was relatively high in group A (5 of 24, 20.8%) and for perforations of stomach (3 of 13, 23.1%) and small intestine (3 of 12, 25.0%); however, there were no significant differences with regard to age or perforation site (P = 0.244, P = 0.122, respectively).
Conclusion:
SGIPs in pediatric patients had diverse clinical features and different perforation patterns according to age group. However, no significant group differences in mortality were found. Thus, favorable results regardless of age can be expected with prompt recognition, medical resuscitation, and adequate surgical management.
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