Related Experiment Video
Updated: Feb 5, 2026
05:16
Sleeve Gastrectomy in Mice using Surgical Clips
Published on: November 14, 2020
7.4K
Re-sleeve Gastrectomy 4 Years Later: Is It Still an Effective Revisional Option?
F De Angelis1, M Avallone2, A Albanese3
1Division of General Surgery & IFSO Bariatric Center of Excellence, Department of Medico-Surgical Sciences and Biotechnology, Hospital ICOT, Sapienza University of Rome, Via F. Faggiana 1668, 04100, Latina, Italy. francescodeangelis7@gmail.com.
Obesity Surgery
|September 6, 2018
Summary
Re-sleeve gastrectomy (rLSG) shows disappointing long-term results, with many patients needing further revisional surgery or experiencing GERD symptoms. Due to these outcomes, rLSG is no longer offered at the participating centers.
Area of Science:
- Bariatric surgery
- Gastroenterology
- Surgical outcomes
Background:
- Laparoscopic sleeve gastrectomy (LSG) is a common bariatric procedure.
- A significant percentage of patients require revisional surgery after LSG.
- Re-sleeve gastrectomy (rLSG) is a potential option for revisional surgery.
Purpose of the Study:
- To evaluate the long-term outcomes of re-sleeve gastrectomy (rLSG).
- To update the 52-month follow-up data for a cohort of rLSG patients.
Main Methods:
- A cohort of 19 patients who underwent rLSG was followed.
- Data from a previous 24-month follow-up was updated to 52 months.
- Outcomes assessed included GERD symptoms, need for further revision, and weight status.
Main Results:
- Only 16 patients completed the 52-month follow-up.
- Nine patients developed GERD symptoms by 36 months.
- Five patients were converted to laparoscopic Roux-en-Y gastric bypass (RYGB), and two to biliopancreatic diversion with duodenal switch (BPD-DS) for weight regain; four remained asymptomatic.
Conclusions:
- Re-sleeve gastrectomy (rLSG) demonstrates unfavorable long-term outcomes.
- High rates of GERD and need for subsequent revisional surgery were observed.
- rLSG is not currently recommended or offered as a revisional procedure at the study centers.
Related Concept Videos
01:23Dipeptidyl Peptidase 4 Inhibitors
679
Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a...
679
02:19Buffer Effectiveness
55.4K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
The buffer capacity is the amount of acid or base that can be added to a given volume...
55.4K
03:26Framing Effects
8.0K
Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in...
8.0K
01:20Amides to Amines: LiAlH4 Reduction
6.3K
Amide reduction with strong reducing agents like lithium aluminum hydride proceeds through a nucleophilic acyl substitution to form amines. Primary, secondary, and tertiary amides yield primary, secondary, and tertiary amines, respectively.
Amide reduction requires two equivalents of the reducing agent, acting as a source of hydride ions. As shown in the figure, the reaction is initiated with a nucleophilic attack by the hydride ion at the carbonyl carbon to form a tetrahedral intermediate.
Amide reduction requires two equivalents of the reducing agent, acting as a source of hydride ions. As shown in the figure, the reaction is initiated with a nucleophilic attack by the hydride ion at the carbonyl carbon to form a tetrahedral intermediate.
6.3K
01:19Piaget's Stage 4 of Cognitive Development
654
The formal operational stage, as described in Piaget's cognitive development theory, begins around age 11 and extends into adulthood. It marks the emergence of advanced cognitive abilities that differentiate adolescent and adult thinking from those of younger children. This stage is characterized by abstract reasoning, hypothetical-deductive reasoning, and a more complex understanding of self and others.
Abstract Reasoning and Hypothetical-Deductive Thinking
Unlike the concrete operational...
Abstract Reasoning and Hypothetical-Deductive Thinking
Unlike the concrete operational...
654
00:55Nitriles to Amines: LiAlH4 Reduction
4.7K
Nitriles are reduced to amines in the presence of strong reducing agents like lithium aluminum hydride through a typical nucleophilic acyl substitution. The reaction requires two equivalents of the reducing agent. The reducing agent acts as a source of hydride ions.
As shown below, the mechanism involves three steps. Firstly, the hydride ion acting as a nucleophile attacks the nitrile carbon to form an anion. In the second step, a second equivalent of the hydride ion attacks the anion to...
As shown below, the mechanism involves three steps. Firstly, the hydride ion acting as a nucleophile attacks the nitrile carbon to form an anion. In the second step, a second equivalent of the hydride ion attacks the anion to...
4.7K