Related Experiment Video
Updated: Feb 5, 2026

Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor IRIS
Published on: May 3, 2011
Signal detection algorithms for interferometric sensors with harmonic phase modulation: miscalibration of modulation
Abstract:
In the current paper, we have developed an analytical apparatus that allows us to calculate the phase error produced by miscalibration of modulation parameters. The case of harmonic modulation is considered, and the analysis is performed for cases of miscalibration for two parameters: amplitude and start phase. Two demodulation algorithms are considered: a conventional 4-point algorithm, based on an ordinary least-squares approach, and a previously developed 4+1 algorithm with high immunity to phase error, induced by change of target phase on the demodulation interval. Predictions, given by developed analytical equations, are verified by means of numeric modeling.
Related Concept Videos
Harmonic Mean
Take the example of the speed of a car, which is the measure of the rate of distance traveled. If the vehicle traverses the same distance back-and-forth, its average speed equals the total distance traveled divided by the total time taken. However, if the car moves with varying speeds, then the arithmetic mean is more skewed...
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Simple Harmonic Motion
Trial and Error and Algorithm
Energy in Simple Harmonic Motion
Phase Diagrams

