Dynamic image denoising for voxel-wise quantification with Statistical Parametric Mapping in molecular neuroimaging

Stergios Tsartsalis1,2,3, Benjamin B Tournier1, Christophe E Graf4

  • 1Division of Adult Psychiatry, Geneva University Hospitals, Geneva, Switzerland.

Plos One
|September 6, 2018
PubMed
Summary

Denoising dynamic brain SPECT and PET images with Factor Analysis (FA) improves the detection of binding differences at the voxel level using Statistical Parametric Mapping (SPM). This noise reduction enhances quantification accuracy and reduces variability in binding potential estimations.

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