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Updated: Feb 5, 2026

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Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
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Correction: Stepwise triple-click functionalization of synthetic peptides
Anna Kovalová1, Radek Pohl1, Milan Vrabel1
1Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, 16610, Prague, Czech Republic. vrabel@uochb.cas.cz.
Organic & Biomolecular Chemistry
|September 6, 2018
Summary
This correction clarifies synthetic peptide functionalization. It addresses errors in the original stepwise triple-click chemistry methods and results.
Area of Science:
- Organic Chemistry
- Biomolecular Chemistry
- Synthetic Chemistry
Background:
- The original study detailed a novel stepwise triple-click functionalization strategy for synthetic peptides.
- Accurate reporting of chemical methodologies and experimental outcomes is crucial in scientific publications.
Purpose of the Study:
- To correct specific errors identified in the original publication regarding the stepwise triple-click functionalization of synthetic peptides.
- To ensure the integrity and reproducibility of the reported synthetic peptide chemistry.
Main Methods:
- Review and re-evaluation of the experimental procedures used for peptide functionalization.
- Correction of data and interpretations presented in the original manuscript.
Main Results:
- Identified and corrected inaccuracies in the description of the stepwise triple-click reaction conditions.
- Revised data pertaining to reaction yields and product characterization.
Conclusions:
- The corrected information ensures the accurate representation of the stepwise triple-click functionalization technique.
- This correction upholds the reliability of synthetic peptide modification research.
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