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Updated: Feb 5, 2026
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Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
Published on: August 28, 2015
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Advances in thermosensitive polymer-grafted platforms for biomedical applications
Phung Ngan Le1, Chan Khon Huynh2, Ngoc Quyen Tran3
1Institute of Research and Development, Duy Tan University, Da Nang City 550000, Viet Nam; Institute of Applied Materials Science, Vietnam Academy of Science and Technology, 1A TL29, District 12, Hochiminh City 700000, Viet Nam.
Summary
Smart polymer materials responding to environmental stimuli are advancing biomedical applications. This review highlights temperature-responsive polymer-grafted nanomaterials and hydrogels for smart drug delivery systems (DDS).
Area of Science:
- Polymer Science and Engineering
- Biomedical Engineering
- Materials Science
Background:
- Smart polymeric materials respond to environmental stimuli like temperature, pH, and light.
- Thermo-responsive polymers, including grafted copolymers, steroids, and polyesters, are key components in advanced functional platforms.
- These materials offer significant improvements over traditional materials for biomedical applications.
Purpose of the Study:
- To review recent advancements in temperature-responsive polymer-grafted nanomaterials and hydrogels for smart drug delivery systems (DDS).
- To highlight the development of novel amphiphilic functional platforms and nature-driven biomaterials.
- To explore the potential of these smart biomaterials in future healthcare solutions.
Main Methods:
- Literature review focusing on temperature-responsive polymer-grafted nanomaterials and hydrogels.
- Analysis of synthetic polymers and nature-driven biomaterials for DDS applications.
- Examination of novel amphiphilic functional platforms.
Main Results:
- Successful clinical trials of thermal-responsive grafted platforms (e.g., ThermoDox®, BIND-014) demonstrate efficacy in drug delivery.
- Development of multifunctional platforms with enhanced functionalities for biomedical use.
- Progress in creating smart biomaterials from diverse polymer types.
Conclusions:
- Temperature-responsive polymer-grafted nanomaterials and hydrogels represent a significant advancement in smart drug delivery systems (DDS).
- These smart biomaterials hold great promise for future human healthcare applications.
- Continued research into synthetic and nature-driven materials will drive innovation in DDS.
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