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Updated: Feb 5, 2026

Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation
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MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network

J J Brudvig1,2, J T Cain1, R M Sears1,2

  • 1Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, 57104, USA.

Scientific Reports
|September 7, 2018
PubMed
Summary

Myristoylated alanine-rich C kinase substrate (MARCKS) is crucial for neuronal differentiation. Lacking MARCKS, neurons show reduced neurite outgrowth and complexity, highlighting its role in neurite initiation.

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