Spontaneous Regression of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus
Related Experiment Video
Updated: Feb 5, 2026

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
Yudai Koya1, Tomohiro Suzuki2, Mayumi Tai2
1Third Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Abstract:
An 83-year-old man underwent transcatheter arterial chemoembolization (TACE) for a 20-mm hepatocellular carcinoma (HCC) in Couinaud's segment 4. Computed tomography (CT) 4 months after TACE showed tumor thrombus in the portal vein in addition to diffuse metastases and arterioportal shunts in the left lobe. Although we performed the best supportive care, the tumor thrombus in the portal vein and tumors in the left lobe had completely disappeared on CT 16 months after the TACE. Rapidly grown portal vein tumor thrombus and arterioportal shunt might be the causes of spontaneous regression of HCC, probably associated with tumor hypoxia.
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