Effect of Carotid Artery Morphological Variations on Cognitive Function.
Lin Chen1, Jialu Huang1, Suxia Wang1,2
1Department of Neurology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Behavioural Neurology
|September 7, 2018
Summary
Carotid artery variations (CAMV) can impact cognition. The K-type CAMV was linked to cognitive impairment, with MoCA tests being more effective than MMSE for detection.
Area of Science:
- Neurology
- Vascular Medicine
- Medical Imaging
Background:
- Carotid artery morphological variations (CAMV) are common findings in medical imaging.
- The impact of CAMV on cognitive function remains largely unexplored.
Purpose of the Study:
- To investigate the potential causal relationship between CAMV and cognitive impairment.
- To determine if specific CAMV types are associated with cognitive deficits.
Main Methods:
- 96 hospitalized patients undergoing digital subtract angiography (DSA) were categorized into non-CAMV, T-type, and K-type groups.
- Cognitive function was assessed using the Mini-Mental State Scale (MMSE), Montreal Cognitive Assessment (MoCA), Verbal Fluency Test (VFT), and Digital Span Test (DST).
Main Results:
- The K-type CAMV group showed significantly higher positive rates on MoCA compared to non-CAMV and T-type groups (p < 0.001).
- VFT and DST scores were significantly lower in the K-type CAMV group than in the non-CAMV and T-type groups (p < 0.001).
- No significant differences in MMSE positive rates were observed among the non-CAMV, T-type, and K-type groups (p = 0.836).
Conclusions:
- K-type CAMV is associated with cognitive impairment.
- The Montreal Cognitive Assessment (MoCA) is more sensitive than the Mini-Mental State Scale (MMSE) for detecting mild cognitive impairment related to CAMV.
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