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A Case of Phlegmonous Gastritis in a Patient with Psoriatic Arthritis on Infliximab

Laurence De Davide1, Annie Beaudoin1

  • 1Department of Gastroenterology, Sherbrooke University Hospital Center, Sherbrooke, QC, Canada.

Case Reports in Gastrointestinal Medicine
|September 7, 2018
PubMed

Insights

Phlegmonous gastritis, a rare but deadly infection, can occur secondary to immunosuppressive therapy. This case highlights a favorable outcome with conservative antibiotic treatment in an immunosuppressed patient.

Area of Science:

  • Gastroenterology
  • Immunology
  • Infectious Diseases

Background:

  • Phlegmonous gastritis is a severe submucosal gastric infection with high mortality.
  • Immunosuppressive therapy, used for conditions like psoriatic arthritis, can increase infection risk.

Observation:

  • A 42-year-old male with psoriatic arthritis on Infliximab presented with symptoms suggestive of phlegmonous gastritis.
  • The patient's condition was attributed to immunosuppressive therapy.

Findings:

  • Diagnosis of phlegmonous gastritis was confirmed.
  • The patient received a 14-day course of broad-spectrum antibiotics.

Implications:

  • Conservative antibiotic therapy can be effective for phlegmonous gastritis in immunosuppressed patients.
  • Early diagnosis and treatment are crucial for improving outcomes in this rare condition.

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