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Updated: Feb 5, 2026

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Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
Published on: March 29, 2022
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Unexpected Genetic Cause in Two Female Siblings with High Myopia and Reduced Visual Acuity
M N Preising1, C Friedburg1, W Bowl1
1Department of Ophthalmology, Justus-Liebig University Giessen, University Medical Center Giessen and Marburg GmbH, Giessen Location, Germany.
Biomed Research International
|September 7, 2018
Summary
This study identifies a novel CACNA1F gene mutation causing congenital stationary night blindness in two young sisters. This research is the first to report biallelic CACNA1F mutations in females with this condition.
Area of Science:
- Ophthalmology
- Genetics
- Neuroscience
Background:
- High myopia often results from uncorrected refractive errors or hereditary retinal conditions.
- The precise mechanisms linking genetic factors to high myopia and retinal degeneration are not fully understood.
- Congenital stationary night blindness (CSNB) is a group of inherited retinal disorders.
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