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Related Experiment Video

Updated: Feb 5, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Sentinel node evaluation in prostate cancer.

Ramkishen Narayanan¹, Timothy G Wilson²

¹John Wayne Cancer Institute at Providence Saint John's Health Center, 2200 Santa Monica Blvd, Suite 131, Santa Monica, CA, 90404, USA. Ramkishen.narayanan@providence.org.

Clinical & Experimental Metastasis

|September 7, 2018

Summary

This summary is machine-generated.

Sentinel lymph node (SLN) biopsy for prostate cancer (PCa) pelvic lymph node dissection (PLND) offers potential benefits but remains investigational. This review explores challenges and solutions for SLN-based PLND in PCa.

Keywords:

Lymph node invasion Lymph node metastasis(es)Lymph node(s)Pelvic lymph node dissection (or pelvic lymphadenectomy)Prostate cancer Sentinel lymph node biopsy Sentinel lymph node dissection Sentinel lymph node(s)

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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Area of Science:

Urology
Oncology
Surgical Innovation

Background:

Pelvic lymph node dissection (PLND) is a standard procedure in radical prostatectomy for prostate cancer (PCa).
Conventional PLND is associated with significant time, cost, and morbidity.
Sentinel lymph node (SLN) biopsy presents a potentially less invasive alternative.

Purpose of the Study:

To review the rationale for PLND in PCa.
To evaluate current investigational efforts in SLN-based PLND for PCa.
To discuss challenges and potential solutions for implementing SLN-based PLND.

Main Methods:

Literature review of studies on SLN biopsy and PLND in PCa.
Analysis of the feasibility and outcomes of SLN-based PLND.
Discussion of the current status and future directions of SLN techniques in PCa management.

Main Results:

The SLN concept for PCa was first reported nearly 20 years ago.
SLN biopsy (single node) or targeted SLN dissection (multiple nodes) is still considered investigational.
SLN-based PLND aims to reduce morbidity compared to conventional PLND.

Conclusions:

SLN-based PLND holds promise for improving outcomes in PCa surgery.
Further research and standardization are needed to establish SLN-based PLND as a routine procedure.
Addressing current challenges is crucial for the successful adoption of SLN techniques in PCa.