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Historical Evolution of the Polymorphous Adenocarcinoma
1Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, FL, USA. juan.hernandez-prera@moffitt.org.
Head and Neck Pathology
|September 7, 2018
Summary
The 2017 WHO classification introduced "cribriform variant of polymorphous adenocarcinoma" to address taxonomic debates. Understanding the historical evolution of polymorphous adenocarcinoma is crucial for pathologists.
Area of Science:
- Pathology
- Oncology
- Head and Neck Tumors
Background:
- The 2017 World Health Organization Classification of Head and Neck Tumors introduced new terminology.
- This aimed to resolve the classification controversy surrounding cribriform adenocarcinoma of the tongue.
Observation:
- The term "cribriform variant of polymorphous adenocarcinoma" was established.
- This nomenclature seeks to unify understanding of related tumors.
Findings:
- Historical context of polymorphous adenocarcinoma (formerly polymorphous "low grade" adenocarcinoma) is essential.
- Reviewing the evolution of these tumors aids in understanding their classification.
Implications:
- Accurate diagnosis and classification of head and neck tumors are critical.
- Pathologists need to understand the historical evolution of tumor nomenclature.
- This review provides insights into the origins and classification of polymorphous adenocarcinoma.
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