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Updated: Feb 5, 2026

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
Published on: September 19, 2013
Immuno-affinity Amperometric Detection of Bacterial Infections
Yingdi Zhu1, Milica Jović1, Andreas Lesch1
1Department of chemistry and chemical engineering, École Polytechnique Fédérale de Lausanne, 1951, Sion, Switzerland.
Abstract:
A combination of an immuno-affinity enrichment strategy and sensitive amperometric read-out was implemented in a point-of-care platform intended for bacterial infection analysis. Bacterial cells, selectively captured and enriched from complex matrices through immuno-affinity, were detected by amperometric monitoring of the redox state of metabolic activity indicators, providing species identification and viable-cell quantification. The method was successfully employed for the diagnosis of bacterial infections including antimicrobial susceptibility testing with only several hours of total working time.
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