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Landiolol: pharmacology and its use for rate control in atrial fibrillation in an emergency setting
Hans Domanovits1, Michael Wolzt2, Günter Stix3
1Department of Emergency Medicine, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, Austria.
Abstract:
This article provides new insight on landiolol, an ultra-short acting injectable betablocker, recently approved in Europe, with regard to its pharmacokinetic and pharmacodynamic profile, along with its first experience in Caucasian healthy volunteers and patients with atrial fibrillation. Landiolol as iv formulation exhibited in an emergency setting rapid rate reduction in patients with tachycardic atrial fibrillation without pronounced blood pressure drop both in caucasian and asian populations in similar manner.
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