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Cognitive-motor interference during gait in patients with Multiple Sclerosis: a mixed methods Systematic Review
B Postigo-Alonso1, A Galvao-Carmona2, I Benítez3
1Department of Psychology, Universidad Loyola Andalucía, Seville, Spain; Human Neuroscience Lab (HNL), Universidad Loyola Andalucía, Seville, Spain.
Neuroscience and Biobehavioral Reviews
|September 7, 2018
Summary
Cognitive-motor interference (CMI) is a key marker for daily impairment in Multiple Sclerosis (MS). Standardized dual tasks, like verbal fluency while walking, can effectively assess CMI in MS patients.
Area of Science:
- Neurology
- Rehabilitation Science
- Human Movement Science
Background:
- Cognitive-motor interference (CMI) is recognized as a significant indicator of functional limitations in Multiple Sclerosis (MS).
- Existing research on CMI in MS is fragmented, necessitating a comprehensive synthesis of evidence.
- This systematic review aims to identify specific variables influencing CMI assessment in MS patients.
Purpose of the Study:
- To systematically review and synthesize existing evidence on cognitive-motor interference (CMI) in Multiple Sclerosis (MS).
- To identify specific motor and cognitive variables that are sensitive and specific indicators of CMI in MS.
- To determine the optimal conditions for assessing CMI as a marker of daily life impairment in MS.
Main Methods:
- A systematic review utilizing a mixed-methods approach.
- Analysis of studies investigating cognitive-motor interference in individuals with Multiple Sclerosis.
- Identification and description of sensitive and specific motor and cognitive variables.
Main Results:
- Multiple Sclerosis patients exhibit significant cognitive-motor interference.
- Key motor variables for detecting CMI include velocity, cadence, and double support time, with double support being specific to MS.
- Cognitive tasks like Alternate Alphabet and Serial Subtracting 7s were sensitive; Verbal Fluency was both sensitive and specific for CMI in MS.
Conclusions:
- Cognitive-motor interference assessment in MS should incorporate standardized dual tasks, such as Verbal Fluency while walking.
- Measuring double support time and its impact on cognitive performance is recommended.
- The clinical utility of CMI for evaluating MS patients is discussed, highlighting its potential as a valuable assessment tool.
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