Related Experiment Video
Updated: Feb 5, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Electrochemotherapy in melanoma patients: a single institution experience
Corrado Caracò1,1, Ugo Marone1,1, Ester Simeone1,1
1Melanoma Department, Istituto Nazionale Tumori 'Fondazione Pascale' Napoli, Italy.
Aim:
This study was undertaken to update the outcome of the treated lesions with electrochemotherapy (ECT) plus intravenous injection of bleomycin in patients with in-transit disease or distant cutaneous metastases in melanoma patients.
Patients & Methods:
89 patients with relapsed and refractory cutaneous melanoma metastases or in-transit disease were submitted to 126 treatments of ECT.
Results:
34 patients (38.2%) had a partial response and 43 had a complete response (48.3%). 12 patients (13.5%) had no change or progressive disease. The objective response rate was 67.5%.
Conclusion:
The favorable outcome obtained in the present study demonstrates that ECT is a reliable, easy, fast and effective procedure showing benefits in terms of curative and palliative treatment for unresectable cutaneous lesions respecting the quality of life.
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