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Selected summary for the 2015 Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE)

Augusto Villanueva1

  • 1Liver Cancer Program, Divisions of Liver Diseases & Hematology/Medical Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, NY 10029, USA.

Hepatic Oncology
|September 8, 2018
PubMed

Insights

Liver cancer is a leading cause of cancer death globally. The 2015 Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE) highlighted recent advancements in managing this complex disease.

Area of Science:

  • Hepatology
  • Oncology
  • Molecular Biology

Background:

  • Liver cancer is the second leading cause of cancer mortality worldwide.
  • Advanced-stage liver cancer has limited treatment options, posing a significant health challenge.
  • Previous molecular therapies post-sorafenib have failed in Phase III trials, and a validated oncogene addiction loop is yet to be identified.

Purpose of the Study:

  • To provide a comprehensive update on liver cancer management and molecular pathogenesis.
  • To foster scientific exchange among international and regional experts in liver cancer.
  • To consolidate the Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE) as a key resource for clinicians and researchers.

Main Methods:

  • The content reflects discussions and presentations from the 2015 APPLE conference.
  • Expert insights and the latest research findings were shared.
  • Focus on clinical management and molecular pathogenesis of liver cancer.

Main Results:

  • The 2015 APPLE meeting offered an outstanding overview of recent developments.
  • Significant advancements in the clinical management of liver cancer were presented.
  • New insights into the molecular pathogenesis of liver cancer were discussed.

Conclusions:

  • Despite challenges, remarkable advancements in liver cancer research and treatment are emerging.
  • The APPLE meeting serves as a crucial platform for disseminating cutting-edge information in the Asia-Pacific region.
  • Continued expert collaboration is vital for addressing the growing burden of liver cancer.

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