Heart-sparing volumetric modulated arc therapy for whole lung irradiation

Alexandros Papachristofilou1, Anna-Lena Hottinger2, Oliver Weinhold2

  • 1Clinic of Radiotherapy and Radiation Oncology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland. alexandros.papachristofilou@usb.ch.

Abstract

Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
348
Arc Length of a Curve01:30

Arc Length of a Curve

In engineering applications like roller coaster design, cable installation, and railway construction, determining the precise length of a curved path is essential. These paths are rarely straight and often follow smooth, continuous curves that require accurate measurement for effective planning.To estimate the length of a curve, the path is initially divided into small segments. Each segment is approximated by a straight line connecting two nearby points on the curve. The sum of these linear...
70
Arc Length Function01:22

Arc Length Function

The arc length function represents the total distance traveled along a smooth curve measured from a fixed starting point to a variable endpoint. For curves that are continuous and differentiable, arc length provides a precise way to quantify distance when straight-line approximations are insufficient.To derive arc length, the curve is divided into many small segments. Each segment is approximated by a straight line whose length depends on the horizontal and vertical changes over that interval.
56
Spare Receptors01:30

Spare Receptors

Some receptors remain unoccupied even when an agonist produces a maximal response. Such empty ones are called spare receptors. In presence of spare receptors the maximum effect of an agonist drug is achieved with fewer than 100% of the receptors being occupied. To determine the presence of spare receptors, scientists often compare the concentration of the drug needed to produce 50% of the maximum effect (EC50) with the concentration of the drug needed to occupy 50% of the receptors (Kd). If the...
4.6K
Arc Length of a Curve: Problem Solving01:21

Arc Length of a Curve: Problem Solving

A high-voltage power line spans a 40-meter horizontal distance between two transmission towers, resulting in a 10-meter vertical sag due to the effects of gravity and thermal expansion. The curve formed by the suspended cable is a catenary, which accurately models the behavior of a uniform, flexible cable under its own weight. Unlike a parabolic shape, the catenary is described by the hyperbolic cosine function and offers a precise representation of the cable's form.In this setup, engineers...
71
Lung Capacity01:47

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.4K