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lncRNA - Long Non-coding RNAs02:39

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RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
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RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA

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Non-coding RNA Resources.

Shangwei Ning1, Xia Li2

  • 1College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China.

Advances in Experimental Medicine and Biology
|September 8, 2018
PubMed
Summary
This summary is machine-generated.

Non-coding RNAs (ncRNAs) play roles in diseases like cancer. This review systematically examines ncRNA databases, offering valuable resources for researchers studying ncRNA-disease associations.

Keywords:
DatabaseDiseaseWeb serverlncRNAmiRNA

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Area of Science:

  • Molecular Biology
  • Genomics
  • Bioinformatics

Background:

  • Non-coding RNAs (ncRNAs) are functional RNA molecules not translated into proteins.
  • Growing evidence links ncRNAs to various diseases, including cancer.
  • Next-generation sequencing (NGS) has rapidly increased the volume of available ncRNA data.

Purpose of the Study:

  • To systematically review existing specialized databases for non-coding RNAs.
  • To provide researchers with a curated list of resources for investigating ncRNA functions.
  • To facilitate the exploration of ncRNA associations with human diseases.

Main Methods:

  • Systematic literature review of ncRNA-related databases.
  • Categorization and description of identified databases.
  • Analysis of database content and accessibility.

Main Results:

  • A comprehensive overview of currently available ncRNA databases.
  • Identification of key features and data types within these databases.
  • Assessment of the utility of these databases for disease research.

Conclusions:

  • Specialized ncRNA databases are crucial resources for scientific inquiry.
  • These databases support further research into the role of ncRNAs in human diseases.
  • The reviewed databases can accelerate discoveries in ncRNA-related pathology.