Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatocellular carcinoma--a clinical study.

T C Lim, L B Teh, K C Kwok

    Annals of the Academy of Medicine, Singapore
    |April 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Incisional Hernia: Plastic Aspects, Component Separation, Technical Details & Pediatrics.

    Hernia : the journal of hernias and abdominal wall surgery·2015
    Same author

    A novel technique with aesthetic considerations in female-to-male transsexuals nipple areola complex reconstruction.

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2013
    Same author

    Ministry of Health clinical practice guidelines: Chronic Hepatitis B Infection.

    Singapore medical journal·2011
    Same author

    Persistent left superior vena cava: a possible site for haemodialysis catheter placement.

    Singapore medical journal·2011
    Same author

    Influence of visual feedback and speed on micromanipulation accuracy.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2009
    Same author

    Non-linear analysis of body responses to functional electrical stimulation on hemiplegic subjects.

    Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine·2009

    Hepatocellular carcinoma predominantly affects Chinese Singaporean males, often presenting with advanced disease and poor survival rates. Early detection and treatment are crucial for improving outcomes in this high-risk population.

    Area of Science:

    • Hepatology
    • Oncology
    • Epidemiology

    Background:

    • Hepatocellular carcinoma (HCC) is a significant health concern, particularly within specific ethnic groups.
    • Understanding the demographic and clinical characteristics of HCC is vital for targeted interventions.

    Purpose of the Study:

    • To describe the epidemiological and clinical features of hepatocellular carcinoma in Chinese Singaporeans.
    • To analyze the diagnostic findings, treatment patterns, and survival outcomes of HCC patients.

    Main Methods:

    • Retrospective analysis of 77 hepatocellular carcinoma patients diagnosed at a Singaporean institution.
    • Review of patient demographics, clinical presentation, laboratory results, imaging findings, treatment received, and survival data.

    Related Experiment Videos

    Main Results:

    • HCC predominantly affected Chinese Singaporean males (97.4%), with peak incidence in the 5th-7th decades.
    • Common symptoms included hepatomegaly (85.7%) and jaundice (63.6%). Abnormal liver function tests (98.7%) and elevated alpha-foetoprotein (79.2%) were frequent.
    • Diagnosis often revealed lesions in both liver lobes (70.1%), with limited surgical resection (5.1%). Survival was poor, with 76.9% dying within six months.

    Conclusions:

    • Hepatocellular carcinoma in Chinese Singaporeans presents with a distinct demographic profile and advanced disease at diagnosis.
    • The study highlights the aggressive nature of HCC in this population and the urgent need for improved early detection and management strategies.