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Updated: Feb 5, 2026

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Pd(II)-Catalyzed [4 + 2] Heterocyclization Sequence for Polyheterocycle Generation

Elizabeth L Glaisyer1, Michael S Watt1, Kevin I Booker-Milburn1

  • 1School of Chemistry , University of Bristol , Cantock's Close , Bristol BS8 1TS , U.K.

Organic Letters
|September 8, 2018
PubMed
Summary

A novel palladium-catalyzed cascade reaction efficiently synthesizes polyheterocycles from simple precursors. This method accommodates diverse indole and pyrrole substrates, showcasing broad applicability in organic synthesis.

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