[RATIO OF PREFRONTAL CORTEX NEURAL ACTIVITY BOTH HEMISPHERES DURING TASK OF CHOICE IN THE TWO-RING MAZE]

Neural activity in two symmetrical areas of the prefrontal cortex left and right hemispheres of the rat brain (55 and 47 neurons, respectively) were recorded during the execution of behavioral tasks in the two-ring maze. Experiments were carried out in two different conditions - task with the key, when only appropriate side to signal was reinforced, and without a key, when any choice was reinforced. Differential neural activity was estimated - the level of difference in firing on the right and left choice. When the animal did not guided by external keys (two behavioral situations: trails in a behavior block without any keys or error trails in behavior block with key presentation) there was observed prevalence of differential activity in the left hemisphere. The prevalence in the right hemisphere was observed in the correct trials in behavior block with key presentation. Apparently this is evidence of the dynamics in the hemispheric balance, depending on the external and internal conditions and the special role of the right hemisphere in the mechanisms of learning and inclusion of external determinants of the adaptive behavior response.