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Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild Traumatic Brain Injury
Angela Lumba-Brown1, Keith Owen Yeates2, Kelly Sarmiento3
1Stanford University School of Medicine, Stanford, California.
Insights
This guideline provides evidence-based recommendations for diagnosing and managing mild traumatic brain injury (mTBI) in children. It addresses best practices for healthcare professionals to improve pediatric concussion care.
Area of Science:
- Pediatric Neurology
- Public Health
- Evidence-Based Medicine
Background:
- Mild traumatic brain injury (mTBI), or concussion, is a growing public health concern in children.
- Emergency department visits for pediatric mTBI have significantly increased over the past decade.
- Currently, no evidence-based clinical guidelines exist for diagnosing and managing pediatric mTBI in the U.S.
Purpose of the Study:
- To develop clinical recommendations for healthcare professionals on diagnosing, prognosing, and managing pediatric mTBI.
- To provide a guideline based on a systematic review of existing literature.
- To establish best practices for pediatric concussion care.
Main Methods:
- A guideline workgroup was established by the CDC.
- Recommendations were drafted based on a systematic review of literature (1990-2015) and expert inference.
- Evidence was assessed to assign levels of obligation (must, should, may) to recommendations.
Main Results:
- The guideline includes 19 sets of recommendations for pediatric mTBI diagnosis, prognosis, and management.
- Recommendations cover imaging, symptom scales, cognitive testing, risk assessment, monitoring, counseling, education, rest, and return-to-school protocols.
- Specific guidance is provided for diagnosis, prognosis, and treatment of pediatric concussion.
Conclusions:
- This guideline identifies current best practices for pediatric mTBI based on available evidence.
- The CDC has developed user-friendly implementation materials to support guideline adoption.
- Ongoing evaluation is crucial to understand the impact and refine recommendations as new evidence emerges.
Importance:
Mild traumatic brain injury (mTBI), or concussion, in children is a rapidly growing public health concern because epidemiologic data indicate a marked increase in the number of emergency department visits for mTBI over the past decade. However, no evidence-based clinical guidelines have been developed to date for diagnosing and managing pediatric mTBI in the United States.
Objective:
To provide a guideline based on a previous systematic review of the literature to obtain and assess evidence toward developing clinical recommendations for health care professionals related to the diagnosis, prognosis, and management/treatment of pediatric mTBI.
Evidence Review:
The Centers for Disease Control and Prevention (CDC) National Center for Injury Prevention and Control Board of Scientific Counselors, a federal advisory committee, established the Pediatric Mild Traumatic Brain Injury Guideline Workgroup. The workgroup drafted recommendations based on the evidence that was obtained and assessed within the systematic review, as well as related evidence, scientific principles, and expert inference. This information includes selected studies published since the evidence review was conducted that were deemed by the workgroup to be relevant to the recommendations. The dates of the initial literature search were January 1, 1990, to November 30, 2012, and the dates of the updated literature search were December 1, 2012, to July 31, 2015.
Findings:
The CDC guideline includes 19 sets of recommendations on the diagnosis, prognosis, and management/treatment of pediatric mTBI that were assigned a level of obligation (ie, must, should, or may) based on confidence in the evidence. Recommendations address imaging, symptom scales, cognitive testing, and standardized assessment for diagnosis; history and risk factor assessment, monitoring, and counseling for prognosis; and patient/family education, rest, support, return to school, and symptom management for treatment.
Conclusions And Relevance:
This guideline identifies the best practices for mTBI based on the current evidence; updates should be made as the body of evidence grows. In addition to the development of the guideline, CDC has created user-friendly guideline implementation materials that are concise and actionable. Evaluation of the guideline and implementation materials is crucial in understanding the influence of the recommendations.
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