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Commentary on the Impact of Obesity on PediatricDiabetes
Sungeeta Agrawal1, Robert Gensure1
1Division of Pediatric Endocrinology, Floating Hospital in children at Tufts Medical Center/Tufts University School of Medicine, Boston, Massachusetts.
Abstract:
While conventionally most children diagnosed with diabetes are thought to have type 1 diabetes mellitus (T1DM), with the increased prevalence of obesity, more are being affected by type 2 (T2) DM. Obesity leads to increased insulin resistance, which over time can lead to progressive β-cell failure and ultimately T2DM. However, patients developing T1DM may also be obese, making both the proper classification and management of diabetes in children more challenging. In this commentary, the authors discuss the impact ofobesity on the presentation of pediatric diabetes, how to differentiate between T1DM and T2DM, and the proper management of both diseases.
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