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Updated: Feb 5, 2026

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
Detection and Treatment of Primary Prostatic Melanoma
Roger Li1, Miao Zhang2, Jonathan J Duplisea1
1Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Objective:
To describe a case of primary melanoma of the prostate gland, then review the published literature of similar cases.
Methods:
Presentation of the clinical course of a 42-year-old man diagnosed with primary melanoma of the prostate after presenting with gross hematuria. Review of published literature.
Results:
Primary melanoma of the genitourinary tract is a very rare disease, representing less than 1% of all melanomas in men. Only 6 cases of primary melanomas have been previously reported in the English literature.
Conclusion:
The current report emphasizes the importance of a multidisciplinary approach and adherence to treatment principles in cutaneous melanoma. With complete surgical extirpation (including extended pelvic lymphadenectomy as needed), close surveillance using 18F-FDG PET/CT, and aggressive systemic treatment in patients with good performance status, cure can be achieved.
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