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Updated: Feb 5, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
A single-institution study of predisposing factors of patients with BAVMs to flow-related aneurysm
Wen-Yuan Yang1, Chao-Bao Luo1, Yuang-Seng Tsuei2
1Department of Radiology, Taipei Veterans General Hospital and National Yang-Ming University, School of Medicine, Taipei, Taiwan; Department of Radiology, Tri-Service General Hospital and National Defenses Medical Center, Taipei, Taiwan.
Background And Purpose:
The goal of this study was to assess the potential risk factors leading to flow-related aneurysm (FA) formation in patients with brain arteriovenous malformations (BAVMs) in Taiwanese.
Methods:
We recruited 890 patients with BAVMs: 72 had FA(s) and 818 did not. Several factors were assessed including patient's age, gender, BAVM volume and location, and Spetzler-Martin grade.
Results:
The 890 patients with BAVM had a mean age of 30 years (range: 2-84), mean BAVM volume of 10.6 mL (range: 0.13-91.4). BAVMs were ruptured in 42% of patients. Compared to BAVM patients without FAs, the 72 patients with FAs had older age (mean 41 yrs vs 31 yrs, p < 0.001); larger average BAVM volume (39.6 mL vs 16.1 mL, p < 0.001). No statistical significance in Spetzler-Martin grades (χ2 value = 8.687 and p = 0.122) was found in terms of formation of FA. FA demonstrated similar gender distribution and BAVM location distribution (the χ2-value was 0.242 and 0.812, respectively).
Conclusion:
Patients with older age and large BAVM volume are more prone to FA. Gender, BAVM location, and BAVM grade are not statistically significant predisposing factors for FA.
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