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Updated: Feb 5, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Emergency trans-catheter coronary intervention for left main compression secondary to pulmonary hypertension in a
Gianfranco Butera1, Nizar Ben Mansour1, Federico De Marco1
1Department of Congenital Cardiology and Cardiac Surgery, IRCCS Policlinico San Donato, Italy.
Insights
A child with severe heart defects experienced ischemic cardiomyopathy due to pulmonary artery compression. A rescue angioplasty successfully treated the blocked coronary artery bypass, improving blood flow.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- A 4-year-old child presented with a large atrial septal defect (ASD) and severe pulmonary hypertension.
- The patient developed ischemic cardiomyopathy, likely caused by left main (LM) coronary artery compression from a dilated pulmonary artery trunk.
Observation:
- Surgical repair of ASD and coronary artery bypass grafting (CABG) did not allow for ECMO weaning.
- Coronary angiography revealed near-occlusion of the left internal mammary artery bypass graft.
Findings:
- A rescue percutaneous intervention was performed on the left main coronary artery.
- Successful implantation of a drug-eluting stent restored LM artery patency.
Implications:
- Percutaneous coronary intervention can be a viable rescue strategy for complex pediatric coronary artery issues.
- This case highlights the challenges in managing severe pulmonary hypertension-related cardiac complications in children.
Abstract:
Here, we report on the case of a 4-year-old child with large atrial septal defect (ASD) and severe pulmonary hypertension presenting an ischemic cardiomyopathy secondary to left main (LM) compression by a dilated pulmonary artery trunk. Despite of surgical treatment consisting in ASD closure and coronary artery bypass grafting, the patient was not weanable from ECMO. Control coronarography showed a near-occlusion of the left mammary bypass. A rescue percutaneous LM angioplasty with drug-eluting stent implantation was performed.
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