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Updated: Feb 5, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
First Human Evaluation of Endothelial Healing after a Pipeline Flex Embolization Device with Shield Technology
Boris Pabón Guerrero1, Carlos Díaz Pacheco1,2, Ahmed Saied3,4
1Angioteam, Angiosur, Medellín, Colombia.
Abstract:
A 64-year-old female presented with an incidentally-discovered right posterior inferior cerebral artery (PICA) aneurysm, initially treated in 2015 by simple coiling. Follow-up demonstrated significant coil compaction that required retreatment. Retreatment was done uneventfully using a Pipeline embolization device (PED) shield deployed starting from the basilar artery and ending at the V4 segment of the vertebral artery. Eight-weeks post-deployment, a follow-up digital subtraction imaging (DSA) and intravascular imaging with optical coherence tomography were obtained. The intravascular imaging demonstrated that the flow diverter had good wall apposition and concentric neointimal growth over the braid with exception to the areas that the PED was not in contact with the endothelial wall, such as at the right PICA ostium and at the vertebrobasilar junction. The entire procedure was safe, and the patient had no complications. In this article, we describe for the first time the assessment of the status of endothelial "healing" of the PED shield at 8-weeks.
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