Exclusive breast feeding and dehydration fever in newborns during the first days of life

Kaitlin M Kenaley1,2, Jay Greenspan1, Zubair H Aghai1

  • 1Division of Pediatrics, Thomas Jefferson University/Nemours, Philadelphia, PA, USA.

Insights

Fever in newborns may indicate dehydration, particularly in exclusively breastfed infants. This study found 71% of febrile infants in the NICU showed signs of dehydration, with no serious infections identified.

Area of Science:

  • Neonatal Medicine
  • Pediatrics
  • Public Health

Background:

  • Fever in newborns is a common reason for admission to the Neonatal Intensive Care Unit (NICU).
  • Differentiating infectious causes from non-infectious causes like dehydration is crucial for appropriate management.

Purpose of the Study:

  • To investigate the prevalence of dehydration fever in infants admitted to the NICU.
  • To identify risk factors and characteristics associated with dehydration in febrile infants.

Main Methods:

  • Retrospective analysis of 75 term infants admitted to the NICU with fever.
  • Infants were classified into dehydration and non-dehydration groups based on clinical and laboratory signs.
  • Comparison of clinical and laboratory variables between the two groups.

Main Results:

  • 71% (53/75) of febrile infants admitted to the NICU exhibited clinical and laboratory signs of dehydration.
  • Dehydration was more prevalent in exclusively breastfed infants and those with fever onset after 24 hours of age.
  • No positive blood or cerebrospinal fluid cultures were found in infants with dehydration, suggesting absence of serious bacterial or viral infections.
  • The incidence of dehydration fever rose significantly after implementing an "Exclusive Breast Feeding" policy.

Conclusions:

  • Dehydration is a significant cause of fever in exclusively breastfed infants during the early neonatal period.
  • Febrile infants with signs of dehydration in this cohort did not have serious bacterial or viral infections.
  • The findings highlight the importance of monitoring hydration status in exclusively breastfed newborns presenting with fever.

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