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Exclusive breast feeding and dehydration fever in newborns during the first days of life
Kaitlin M Kenaley1,2, Jay Greenspan1, Zubair H Aghai1
1Division of Pediatrics, Thomas Jefferson University/Nemours, Philadelphia, PA, USA.
Insights
Fever in newborns may indicate dehydration, particularly in exclusively breastfed infants. This study found 71% of febrile infants in the NICU showed signs of dehydration, with no serious infections identified.
Area of Science:
- Neonatal Medicine
- Pediatrics
- Public Health
Background:
- Fever in newborns is a common reason for admission to the Neonatal Intensive Care Unit (NICU).
- Differentiating infectious causes from non-infectious causes like dehydration is crucial for appropriate management.
Purpose of the Study:
- To investigate the prevalence of dehydration fever in infants admitted to the NICU.
- To identify risk factors and characteristics associated with dehydration in febrile infants.
Main Methods:
- Retrospective analysis of 75 term infants admitted to the NICU with fever.
- Infants were classified into dehydration and non-dehydration groups based on clinical and laboratory signs.
- Comparison of clinical and laboratory variables between the two groups.
Main Results:
- 71% (53/75) of febrile infants admitted to the NICU exhibited clinical and laboratory signs of dehydration.
- Dehydration was more prevalent in exclusively breastfed infants and those with fever onset after 24 hours of age.
- No positive blood or cerebrospinal fluid cultures were found in infants with dehydration, suggesting absence of serious bacterial or viral infections.
- The incidence of dehydration fever rose significantly after implementing an "Exclusive Breast Feeding" policy.
Conclusions:
- Dehydration is a significant cause of fever in exclusively breastfed infants during the early neonatal period.
- Febrile infants with signs of dehydration in this cohort did not have serious bacterial or viral infections.
- The findings highlight the importance of monitoring hydration status in exclusively breastfed newborns presenting with fever.
Abstract:
Objectives: To determine the prevalence of dehydration fever in infants admitted to the Neonatal Intensive Care Unit (NICU) from the well newborn nursery with fever in the first days of life.Study design: Retrospective data analysis of term infants admitted to the NICU from the well newborn nursery with fever (n = 75). Infants were divided into two groups based on hydration status using clinical and laboratory signs of dehydration. Clinical and laboratory variables were compared between the two groups.Results: Fifty-three of the 75 infants admitted to the NICU with fever had clinical and laboratory signs of dehydration (71%). Infants with dehydration were more likely to be exclusively breast fed and present with fever at >24 h of age. There were no positive blood or cerebrospinal fluid cultures in infants with dehydration. The incidence of dehydration fever increased after implementation of an "Exclusive Breast Feeding" policy from 1.4/1000 to 3.5/1000 live births (p ≤ .01).Conclusions: Dehydration is associated with fever in exclusively breast fed infants during the first several days of life. There were no cases of serious bacterial or viral infections in the cohort of febrile infants with clinical and laboratory signs of dehydration.
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