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Dr. Lupattelli et al. Reply.
Angela Lupattelli1, Hedvig Nordeng2
1PharmacoEpidemiology and Drug Safety Research Group, School of Pharmacy, and PharmaTox Strategic Research Initiative, University of Oslo, Norway.
Journal of the American Academy of Child and Adolescent Psychiatry
|September 11, 2018
Summary
Prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) can impact child development. Our study examined time-dependent effects on behavioral, emotional, and social outcomes at age five.
Area of Science:
- Neuroscience
- Developmental Psychology
- Pharmacology
Background:
- Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed during pregnancy.
- Understanding the long-term neurodevelopmental effects of prenatal SSRI exposure is crucial.
Discussion:
- This response addresses a Letter to the Editor regarding our study on prenatal SSRI exposure.
- Key methodological questions concerning the classification of exposure windows are discussed.
Key Insights:
- Prenatal SSRI exposure demonstrates time-dependent effects on offspring development.
- Offspring outcomes at age five encompass behavioral, emotional, and social domains.
Outlook:
- Further research is needed to refine understanding of SSRI exposure windows.
- Continued investigation into the nuanced impacts of psychotropic medication during gestation is warranted.

