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Updated: Feb 5, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Correlations between peripapillary retinal nerve fiber layer thickness and macular thickness in different various
M Sánchez-Pulgarín1, F Saenz-Frances2, J M Martinez-de-la-Casa2
1Hospital Universitario Rey Juan Carlos, Madrid, Spain.
Purpose:
To determine the relationship between macular thickness and peripapillary retinal nerve fiber layer (RNFLp) thickness in different stages of primary open-angle glaucoma (POAG).
Methods:
Ninety prospectively selected patients with different stage POAG underwent spectral domain optical coherence tomography (SD-OCT) to determine macular and RNFLp thicknesses in different regions and sectors respectively. Correlations were then established through Pearson's correlation coefficient between RNFLp and macular thicknesses in the different disease stages.
Results:
Greatest correlation was observed between the inferior RNFLp sector and the internal inferior macula both in the whole patient population and in the subset of patients with incipient glaucoma.
Conclusions:
When the optic nerve disc is affected by another condition, macular thickness determination may help detect POAG and monitor its progression.
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