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Related Concept Videos

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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Endotracheal Intubation II: Nursing Management01:17

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Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
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Related Experiment Video

Updated: Feb 5, 2026

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

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Thyroid storm following rapid sequence intubation.

Walker Pride1, Alexander Smith2, Ryan Joseph2

  • 1University of Texas Health Science Center at San Antonio, United States of America.

The American Journal of Emergency Medicine
|September 11, 2018
PubMed
Summary
This summary is machine-generated.

Thyroid storm, a rare but life-threatening condition, can be triggered by various stressors. This case highlights rapid sequence intubation as a potential precipitant, emphasizing the need for prompt diagnosis and treatment.

Keywords:
AdderallAttention deficit hyperactivity disorderEtomidateFentanylGraves diseaseHyperthyroidismMidazalomModerate sedationProcedural sedationPropofolRapid sequence intubationRocuroniumThyroid storm

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Area of Science:

  • Endocrinology
  • Critical Care Medicine

Background:

  • Thyroid storm is a severe, life-threatening exacerbation of thyrotoxicosis.
  • It has an estimated incidence of 0.61–0.76 per 100,000 people.
  • Mortality can reach up to 30% without prompt intervention.

Observation:

  • A 46-year-old male presented with symptoms suggestive of food impaction.
  • The patient experienced severe hypertension, tachycardia, and diaphoresis immediately after rapid sequence intubation (RSI).

Findings:

  • The patient's acute symptoms were diagnosed as thyroid storm.
  • Rapid sequence intubation (RSI) was identified as the likely trigger for the thyroid storm.

Implications:

  • This case underscores the importance of recognizing thyroid storm in patients presenting with critical illness after intubation.
  • Clinicians should consider thyroid storm in the differential diagnosis for patients with unexplained hemodynamic instability post-RSI.
  • Early recognition and management of thyroid storm are crucial for improving patient outcomes and reducing mortality.