Related Experiment Video
Updated: Feb 5, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
[Black henna tattoo: risk of developing allergic contact eczema]
Ouiam El Anzi1, Badreddine Hassam1
1Service de Dermatologie et Vénérologie, Centre Hospitalier Universitaire IBN SINA, Faculté de Médecine et de Pharmacie, Université Mohammed V, Rabat, Maroc.
Abstract:
Henna is used for coloring hair, but also to draw labile skin tattoo. Henna is often mixed with paraphenylenediamine (PPD). We report the case of a female patient presenting with contact eczema due to labile tattoo containing PPD. The study involved a 23-year old young woman with an aesthetic Black Henna tattoo on the back of the hand and on the forearm. This labile tattoo contained PPD. Two days later, the patient developed intensely pruritic, burning erythematovesiculosus and edematous lesions. The lesions involved the tattooed area, corresponding with the original drawing. The lesions were improved using Class 1 of topical corticosteroids (Clobetasol propionate). The patient refused allergy patch testing, so no allergy test was performed. Now, henna is very popular in the western countries. PPD is added to reduce the fixing time or to obtain a darker coloration. It can result in severe systemic reactions. The most frequent allergic reaction is contact dermatitis. Treatment is based on local corticosteroid therapy. A better regulation on labile tattoo, the control of preparations as well as a regular annual information for the general public are essential. The interest of our study lies in highlighting the importance of informing, especially young people, on the risks of labile tattoo.
Related Concept Videos
Allergic Reactions
Detection of Black Holes
Their closest cousins are neutron stars, which are composed almost entirely of neutrons packed against each other, making them extremely dense. A neutron star has the same mass as the Sun but its diameter is only a few kilometers. Therefore, the escape velocity from their surface is close to the speed of light.
Not until the 1960s, when the first neutron...
Allergic Drug Reactions
Contact Angle
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
Contact-dependent Signaling
Gap Junctions
In animal cells, gap junctions are formed...
Relative Risk

