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Nail Sarcoidosis Presenting with Longitudinal Erythronychia
Paula P M van Lümig1, Marcel C Pasch1
1Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Skin Appendage Disorders
|September 11, 2018
Summary
Longitudinal erythronychia, a nail finding, can indicate nail sarcoidosis. Early diagnosis and screening for systemic involvement are crucial for effective management of this chronic condition.
Area of Science:
- Dermatology
- Rheumatology
- Pathology
Background:
- Sarcoidosis is a multisystem inflammatory disease.
- Nail involvement in sarcoidosis is uncommon and can present with varied clinical features.
- Longitudinal erythronychia has not been previously described as a presentation of nail sarcoidosis.
Purpose of the Study:
- To report a unique case of nail sarcoidosis presenting with longitudinal erythronychia.
- To highlight the diagnostic importance of nail matrix biopsy in suspected cases.
- To emphasize the need for screening for systemic and bone involvement in nail sarcoidosis.
Main Methods:
- Clinical presentation review of a 37-year-old woman with toenail abnormalities.
- Histopathological examination of nail matrix biopsy showing granulomas.
- Assessment of patient's history of pulmonary and nasal sarcoidosis.
Main Results:
- Diagnosis of nail sarcoidosis confirmed by histopathology.
- Successful treatment of nail changes with intralesional triamcinolone acetonide.
- Longitudinal erythronychia identified as a potential new clinical sign for nail sarcoidosis.
Conclusions:
- Longitudinal erythronychia may be an early clinical manifestation of nail sarcoidosis.
- Nail sarcoidosis often indicates chronic and systemic disease, potentially involving bones.
- Screening for systemic and bone involvement is essential for comprehensive patient management.
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